Published in Gene Therapy Weekly, April 20th, 2006
"We have used adenovirus-mediated gene transfer and bolus injection of purified apolipoprotein E (apoE) in mice to determine the contribution of LDL receptor family members in the clearance of apoE-containing lipoproteins in vivo and the factors that trigger hypertriglyceridemia," wrote K.E. Kypreos and colleagues, Boston University.
They explained, "A low dose [5 x 108 plaque-forming units (pfu)] of an adenovirus expressing apoE4 did not normalize plasma...
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