Apoptosis
Neuronal apoptosis involves Bid cleavage and translocation to mitochondria
Published in Gene Therapy Weekly, April 20th, 2006
"Bcl-2 homology domain (BH) 3-only proteins couple stress signals to evolutionarily conserved mitochondrial apoptotic pathways. Caspase 8-mediated cleavage of the BH3-only protein Bid into a truncated protein (tBid) and subsequent translocation of tBid to mitochondria has been implicated in death receptor signaling.
"We utilized a recombinant fluorescence resonance energy transfer (FRET) Bid probe to determine the kinetics of...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2006-04-20)
More Articles from Gene Therapy Weekly
- Cancer Gene Therapy
Isoform-specific silencing defines Livin beta as key mediator of apoptosis inhibition - Gene Silencing
Imprinting control region affects the expression of Gnas cluster transcripts - Genetics & Genomics
MUC5AC gene expression in human lung epithelial cells is medicated by dexamethasone - Vector Development
Human peritoneal mesothelial cell growth factor expression is inhibited by shRNA - Adverse Drug Reaction
Adverse effects are associated with bone morphogenetic protein-2 use - Allergy & Immunology
An immunoadjuvant chaperone induces signals upon dendritic cell interaction - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
