Antisense Technology
Antisense oligodeoxynucleotides can be delivered from cationically modified polymer films
Published in Gene Therapy Weekly, May 11th, 2006
"Antisense strategy is a promising approach for the prevention of in-stent restenosis if therapeutic agents such as antisense oligodeoxynucleotides (AS-ODNs) can be successfully delivered to the implant site. Optimizing the routes and conditions for controlled loading and release of therapeutic agents from a biocompatible polymer coating is still required," wrote Z.Q. Zhang and colleagues, University of Manchester. "In this study, PC polymer films bearing different cationic charge densities were...
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Source: Gene Therapy Weekly (2006-05-11)
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