Alveolar Cancer
Bronchoalveolar cell carcinoma is reduced by gene-modified dendritic cells
Published in Gene Therapy Weekly, May 11th, 2006
"The antitumor efficiency of DCs transduced with an adenovirus vector expressing secondary lymphoid chemokine (CCL21) was evaluated in a murine model of spontaneous bronchoalveolar cell carcinoma," wrote S.C. Yang and colleagues, University of California, Los Angeles.
They added, "The transgenic mice (CC-10 TAg) express the SV40 large T antigen (TAg) under the Clara cell promoter, develop bilateral, multifocal, and pulmonary adenocarcinomas, and die at 4...
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Source: Gene Therapy Weekly (2006-05-11)
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