Gene Therapy Weekly

Bloom Syndrome - Bloom syndrome gene expression silenced in human cells by gene targeting

Diabetes Gene Therapy - Type 1 diabetes genetic susceptibility is demonstrated by in vivo RNA interference

Epstein-Barr Virus - EBV antigens are re-targeted by T cells following TCR gene transfer

Gene Research - Mouse study reveals human gene therapy may pose substantial cancer risk

Neuroscience - Learning is impaired by NMDAR1 subunit knock-down in hippocampal neurons

Accreditation - CombiMatrix Molecular Diagnostics receives accreditation from CAP

Acute Myeloid Leukemia - Myeloid HSCs with minimal lymphopoietic potential may be AML transformation site

Addiction Medicine - Opioid-induced regulation of gene expression occurs following mu-opioid receptor transfection

Aneurysms - Cerebral artery aneurysm wall remodeling involves various growth factors

Angiology - Neointima formation is induced by transforming growth factor beta 1

Angiology - Vascular smooth muscle cell receptor-mediated calcium mobilization can be inhibited

Apoptosis - Antianoikis is affected by up-regulated expression of osteoprotegerin, BCL-2, and IAP-1

Apoptosis - Apoptosis is influenced by DNA damage-induced expression of p53

Apoptosis - Glucocorticoid-induced apoptosis is mediated by thioredoxin-interacting protein

Autoimmune Research - McGill describes gene in 20% of people of African descent that shuts down immune system

Avian Influenza - GEN ID Lab Services, Inc. to identify molecules for treating human infections of avian flu

Awards - MIV Therapeutics named to top 100 nanotech companies list by international association

Bacteriology - Chimeric gene expression protects from lethal Escherichia coli infection

Brain Cancer - St. Jude researchers use biochemical pathways to identify correct drug for medulloblastoma

Breast Cancer - Recent studies from the United States and Poland add new data to breast cancer research

Breast Cancer - Research from the People's Republic of China, South Korea and Singapore add new data to breast cancer body of knowledge

Breast Cancer - Researchers from Canada, Switzerland and the United States provide details of new studies and findings in the area of breast cancer

Breast Cancer Vaccine - Breast cancer vaccine plasmid DNA delivery systems were evaluated

Business & Finance - Genzyme sees net income rise in first quarter

Business Update - ExonHit expands Splicearray Line on Affymetrix microarray platform

Cancer Gene Therapy - Cervical cancer HPV16 oncogene silencing is affected by RNA interference

Cancer Gene Therapy - Osteosarcoma treated by adenovirus-mediated p53 gene therapy

Cancer Gene Therapy - Paclitaxel-induced apoptosis in lung cancer cells is enhanced by FHIT protein

Cancer Gene Therapy - Squamous cell carcinoma is inhibited by cationized gelatin delivery of siRNA

Cancer Gene Therapy - Tumor cell motility is modulated by MAP4K4 promigratory kinase

Cancer Genetics - Simian virus 40 small tumor antigen activates Notch, Hedgehog, and Wnt signaling

Cancer Research - Researchers' findings from Australia and the United States advance cancer research

Cancer Therapy - Cancer cell mitochondria targeted by marine antitumor drug lamellarin D

Cancer Therapy - Cell adhesion and motility are influenced by integrin alpha 2-mediated ERK and calpain activation

Cancer Treatment - Findings from the United States and United Kingdom in cancer treatment provide new insights

Cancer Treatment - Researchers from the United States and Canada report details of new studies and findings in the area of cancer treatment

Cancer Treatment - Researchers from the United States, Japan and Greece provide details of new studies and findings in the area of cancer treatment

Cancer Treatment - Studies from the United States, Japan and Korea add new findings to cancer treatment body of knowledge

Cancer Vaccine - Interleukin-expressing tumor membrane vesicles induce T cell proliferation

Cardiology - New findings in cardiology described from Germany and the United Kingdom

Cardiology - Research from Japan and Italy in cardiology provides new insights

Cell Differentiation - Osteoblast differentiation is inhibited by lymphocyte enhancer-binding factor 1 (Lef1)

Cell Growth - Hepatocyte contact inhibition is regulated by growth factor-phosphatase association

Clinical Trials - GenoMed to offer free clinical trial for mumps

Clinical Trials - Lorus announces down regulation of GTI-2040 molecular target in breast cancer clinical study

Collaborations - Digene announces agreement with Asuragen, Inc. for cystic fibrosis screening products

Colorectal Cancer - Colorectal cancer c-fes protein-Tyr kinase functions in growth suppression

Colorectal Cancer - Colorectal carcinoma overexpressed lysosomal enzymes are involved in neuronal ceroid lipofuscinosis

DNA - Findings from the United States and the Netherlands in DNA provide new insights

Dengue Fever - Researchers from the United States and India describe findings in dengue fever studies

Developmental Biology - Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation

Developmental Biology - Maternal imprinting depends on oocyte growth

Diabetes - Reports from Italy, the United Kingdom and Germany add new data to diabetes research

Diabetes Genetics - Diabetic rat proximal tubular cell osteopontin gene expression upregulation revealed

Diabetes Therapy - Diabetes gene therapy is possible by injection of lentivirus containing insulin gene

Drug Delivery - Drug delivery by prototype multifunctional nonconjugate explored

Drug Delivery - Targeted cancer drug delivery achieved using paclitaxel-loaded nanoparticles

Drug Delivery - Targeted drug delivery achieved using a hemoglobin-ribavirin conjugate

Entamoeba Histolytica - Blockage of Entamoeba histolytica cysteine proteases inhibits colonic mucus degradation

Epilepsy - Epilepsy seizure severity is reduced by a ketogenic diet and norepinephrine transporter knockout

Genetics - New data from Japan, the United States and Iceland lluminates research in genetics

Genetics - Researchers from the United States, France and Canada describe findings in genetics studies

Genetics & Genomics - Bone sialoprotein gene transcription is suppressed by chlorpromazine

Genetics & Genomics - Calcitonin receptor-like receptor gene defect causes embryonic lethality in mice

Genetics & Genomics - Codon Devices successfully completes significant NIH pilot

Genetics & Genomics - Macrophage inflammatory gene expression regulated by orphan nuclear receptor