Published in Gene Therapy Weekly, May 18th, 2006
In a groundbreaking new study published recently in Nature, the team that first discovered the role of caspase-12 in humans has now uncovered the mechanism by which it sabotages, allowing researchers to develop methods to counter its damaging effects.
Caspase-12 is found in around 20% of people of African descent, but was entirely lost from all other ethnicities around 60,000 years ago. "It's a mystery why only African populations retained this enzyme," said Dr. Maya Saleh, a medical...
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