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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . May 25th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Geriatrics - Somatic gene transfer of CREB attenuates memory impairment in aging rats

Hepatitis C Virus - Alpha-glucosidase inhibitors restrict binding properties of HCV-like particles

Neuroscience - Thermal hyperalgesia is aggravated by down-regulation of GFR alpha-1 expression

Virology - Dengue virus resistance engineered in genetically modified Aedes aegypti

Adenocarcinoma - Lung adenocarcinoma cells may be targeted by short hairpin RNA targeting EGFR

Adenoviral Vector - Replication properties of human adenovirus in different animal species described

Allergy & Immunology - T cell factors are required for collagen type I-mediated activation of ERK/MAP kinase

Alzheimer Disease - NF-kappa B pathway can be targeted to prevent beta-amyloid-induced neuronal damage

Apoptosis - Induced apoptosis protection of INS-1 cells conferred by mitochondria targeting

Apoptosis - Mitochondrial dysfunction and apoptosis involves nitric oxide-induced mtDNA damage

Apoptosis - Studies from Canada and the United Kingdom add new findings to apoptosis body of knowledge

Autoimmune Diseases - Development of testicular inflammation involves proteinase-activated receptor-2

Autoimmune Diseases - T cell interleukin-17 production is divergently affected by other interleukins

Breast Cancer - Breast cancer cell proliferation is inhibited by ritonavir

Breast Cancer - Recent findings from the United States, Netherlands; p and Switzerland illuminate research in breast cancer

Breast Cancer - Reports from the United Kingdom, DK-2100 Copenhagen; jorgen@cancer and United States add new data to breast cancer research

Business Update - Dermisonics, Inc. prepares U-Strip Ultrasonic transducer device for mass production

Cancer Gene Therapy - Adenovirus-mediated gene delivery inhibits nasopharyngeal tumor growth

Cancer Gene Therapy - Antitumor prodrug gene therapy is enhanced using a low Km cyclophosphamide

Cancer Gene Therapy - Mesenchymal progenitor cells deliver oncolytic adenoviruses

Cancer Gene Therapy - Prostate cancer can be treated via adenovirus combination therapy

Cancer Gene Therapy - Tumor-specific apoptotic gene targeting overcomes radiation resistance in esophageal adenocarcinoma

Cancer Research - Data from South Korea and Germany advance knowledge in cancer research

Cancer Research - New data from the United States and Canada lluminates research in cancer

Cancer Research - Recent studies from the United States add new data to cancer research

Cancer Research - Reports from Japan, Germany and the United States advance knowledge in cancer research

Cancer Research - Reports from Japan, the Netherlands; cjlm and Australia add new data to cancer research

Cancer Research - Studies from Netherlands, United States and Germany describe new findings in cancer research

Cancer Research - Two ChondroGene abstracts on colon and prostate cancer accepted by ASCO

Cancer Therapy - Aplidin oxidizes and inactivates a low molecular weight protein Tyr phosphatase

Cancer Therapy - Dual ovarian cancer therapy is achieved using measles virus

Cancer Therapy - Episomal vectors induce somatic hypermutation in Burkitt-Lymphoma cell lines

Cancer Therapy - Glioblastoma cells are synergistically affected by inhibition of two pathways

Cancer Treatment - Data from Japan and the United States advance knowledge in cancer treatment research

Cancer Treatment - Data from the United States, Italy and Germany advance knowledge in cancer treatment research

Cancer Treatment - Recent findings in cancer treatment described by researchers from Spain, Austria and the United States

Cancer Treatment - Researchers from the United Kingdom, United States and Japan provide details of new studies and findings in the area of cancer treatment

Cardiology - ADAMTS13 metalloprotease displays systemic antithrombotic effects

Cardiology - Angiogenic suicide gene cell therapy regulates the effect of angiogenesis in infarcted hearts

Cardiology - Phosphodiesterase 1A functions in vascular smooth muscle cell growth and survival

Cardiology - Researchers from Germany and the United States report recent findings in cardiology

Cardiology - Studies from the United States and France advance knowledge in cardiology research

Cell Physiology - Cell radioresistance is transiently enhanced by Hsf1-mediated stress response

Cell Physiology - Myoblast attachment and spreading are differentially regulated by ubiquitous calpains

Cervical Cancer - Cervical cancer cells can be sensitized to rhTRAIL-induced apoptosis

Cholera - Cholera toxin A1(3) subdomain is required for full toxic activity

Clinical Trials - Isis reports positive phase 2 data from trials of antisense drug to reduce cholesterol

Clinical Trials - Lilly, Alkermes initiate phase 3 study for inhaled insulin to treat type 1 and 2 diabetes

Clinical Trials - Positive trial data reported for HPV therapeutic vaccine in precancerous cervical lesions

Collaborations - Chemicon International and Australian Stem Cell Centre announce exclusive stem cell agreement

Colorectal Cancer - Colorectal cancer is associated with germline mutations of the MUTYH gene

DNA - New research from Chile, Germany and the United States in the area of DNA detailed

DNA - Recent findings from the United States illuminate research in DNA

DNA - Reports from Germany and the United States add new data to DNA research

DNA - Researchers from Denmark and the United States publish new studies and findings in the area of DNA

DNA - Researchers from Sweden, Japan and the United Kingdom report details of new studies and findings in the area of DNA

DNA - Researchers from Turkey, Japan and Germany provide details of new studies and findings in the area of DNA

DNA Research - Gene silencing mimics human SPINK1 pancreatic phenotype

DNA Vaccine - Cylindrical micelles embedded in DNA lattice developed for gene delivery

Developmental Biology -  Xenopus laevis lens and retina development requires neuronal Leu-rich repeat

Developmental Biology - Embryonic growth-associated protein is essential for vascular development

Developmental Biology - Functions of beta integrins are differentially regulated

Developmental Biology - Long-range upstream and downstream enhancers control Sox9 expression pattern

Developmental Biology - Neural-cell adhesion molecule expression favors endothelial cell organization

Developmental Biology - Rac GTPase activation enhances CD44 cleavage by metalloproteinase disintegrin

Drug Delivery - Biodegradable hydrogel delivers local insulin-like growth factor to cochleae

Drug Development - CepTor presents statistically significant proof of concept data on Myodur for muscular dystrophy

Endometrial Cancer - Hormone-related gene regulation profiles clarified in human endometrial cancer Ishikawa H cells

Escherichia Coli - Enterotoxigenic Escherichia coli two-partner secretion locus identified

Gastric Cancer - Gastric cancer expression of hiwi gene linked to cell proliferation

Gene Therapy - Researchers from Japan, the United States and Germany publish new studies and findings in the area of gene therapy

Genetics - Researchers' data from Germany, the United States and the South Africa advance genetics research

Genetics & Genomics - Clinical data validate genetic biomarker for risk of clozapine-induced agranulocytosis

Genetics & Genomics - Novel PPAR gamma target genes identified in primary human adipocytes

Genetics & Genomics - Period1 gene constitutive expression in rats impairs behavioral and molecular circadian rhythms

Genetics & Genomics - Transgenic mice and rabbits can be produced using DMSO-sperm mediated exogenous DNA transfer

HIV/AIDS - Reports from the United States and Canada add new data to HIV/AIDS research

Hepatitis B Virus - Researchers from Japan, France and the People's Republic of China describe findings in hepatitis B virus studies

Hepatocellular Carcinoma - Findings from the People's Republic of China, Taiwan and United States in hepatocellular carcinoma provide new insights

Hepatocellular Carcinoma - New findings in hepatocellular carcinoma described from Taiwan, Japan and the People's Republic of China

Hyperoxia - Endothelial Akt activation by hyperoxia protects cell mitochondria

Imaging - Luminescent imaging of beta-galactosidase activity achieved in living subjects

Immunotherapy - HSP72 surface expression facilitates gamma delta T cell-mediated killing

Immunotherapy - Third heparin-binding site localized in human complement regulator factor

Infant Leukemia - Low-dose etoposide induces mixed lineage leukemia rearrangement in fetal stem cells

Leukemia - Recent findings in leukemia described by researchers from Japan and the United States

Leukemia - Researchers from Italy and Japan report details of new studies and findings in the area of leukemia

Liver Injury - Hepatic fibrosis and myofibroblast activation are regulated by galectin

Macular Degeneration - Age-related macular degeneration due to choroidal neovascularization modeled

Malaria - Malaria parasite infection is treated by a mosquito 2-Cys peroxiredoxin

Neurology - Findings from Germany, Italy and the United States in neurology provide new insights

Neurology - Recent studies from the United States and Italy add new data to neurology research

Neurology - Research from the United States and Portugal in neurology provides new insights

Neurology - Researchers from the United States, Scotland and Canada detail new studies and findings in the area of neurology

Neuroscience - Neuregulin gene splicing form is involved in oligodendrocyte survival

Pain Management - Mas-related gene-X1 receptor antagonists identified

Pancreatic Cancer - Pancreatic cancer genistein activity is mediated via Notch-1 signaling pathway

Pancreatic Cancer - Pancreatic cancer inhibition partially results from down-regulation of Notch-1

Patents - DNAPrint Genomics receives notice of allowance for patent for identifying genetic links

Physiology - Inducible nitric-oxide synthase gene participates in negative feedback of PARP-1

Pregnancy - Natural killer T cell-mediated pregnancy loss displays gestation stage-dependent mechanisms

Prostate Cancer - Reports from the United States and People's Republic of China add new data to prostate cancer research

Protein Engineering - Immunomedics and IBC Pharmaceuticals announce protein engineering platform technology

Proteomics - Gastric cancer multidrug resistance probed by proteome analysis

Reproduction - Gene expression at the embryo implantation site analyzed serially

Respiratory Medicine - Respiratory distress syndrome involves functional and trafficking defects

Staphylococcus Aureus -  Streptococcus aureus binding of lysostaphin is mediated by cross-linked peptidoglycan

Stem Cell Research - Cytori studies using adipose stem and regenerative cells in breast reconstruction

Stem Cell Research - Stem cell leukemia expressed in bone primordia during embryonic development

Stem Cell Research - Transcription factor MEF/ELF4 regulates quiescence of primitive hematopoietic cells

Tumor Angiogenesis - Angiogenic burst within the tumor microenvironment interrupts tumor dormancy

Tumorigenesis - Protein ENH functions as a sequestration factor in normal and tumor cells

Tumorigenesis - TGF-beta induces TIMP-1 expression in fibrosarcoma cells

Vaccines - Researchers from the United States and United Kingdom report details of new studies and findings in the area of vaccines

Vector Development - Peptide insertion library allows enhanced purification of retroviral and lentiviral vectors

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