Published in Gene Therapy Weekly, May 25th, 2006
Study 1: According to recently published research from the United States, in vitro efficacy of adenovirus expressing TNF-related apoptosis-inducing ligand (AdTRAIL) gene therapy of bladder cancer is enhanced by trichostatin A-mediated restoration of coxsackie and adenovirus receptor (CAR) expression and downregulation of cFLIP and Bcl-X-L.
"Current therapies for bladder cancer are suboptimal and adenoviral gene therapy has been explored as an alternative treatment. In this study, we evaluated the in vitro efficacy of AdTRAIL," wrote A. Elzawahry and colleagues, Medical University of...
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