DNA
Reports from Germany and the United States add new data to DNA research
Published in Gene Therapy Weekly, May 25th, 2006
Study 1: A study from Germany has described nano-carriers for DNA delivery to the lung based upon a covalently-coupled TAT-derived peptide.
"Gene therapy aimed at the respiratory epithelium holds therapeutic potential for diseases such as cystic fibrosis and lung cancer. Polyethylenimine (PEI) has been utilized for gene delivery to the airways."
"In this study," wrote E. Kleemann and colleagues, University of Marburg, "we describe a new modification of PEI, in which an oligopeptide related to the protein transduction domain of HIV-1 TAT was covalently coupled...
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Source: Gene Therapy Weekly (2006-05-25)
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