Developmental Biology
Osteoblastic differentiation markers altered by connexin43 modulation
Published in Gene Therapy Weekly, June 1st, 2006
"Gap junctional channels between cells provide a pathway for exchange of regulatory ions and small molecules. We previously demonstrated that expression of connexins and cell-to-cell communication parallel osteoblastic differentiation and that nonspecific pharmacological inhibitors of gap junctional communication inhibit alkaline phosphatase activity," wrote Z.Y. Li and colleagues, Pennsylvania State University.
"In this study, we stably...
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Source: Gene Therapy Weekly (2006-06-01)
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