Hepatitis B Virus
HBV gene expression and replication are inhibited by stable RNA interference
Published in Gene Therapy Weekly, June 1st, 2006
"HBV infection is a world-wide health problem. Recent studies have demonstrated the efficacy of RNAi against HBV replication at cell culture and animal levels using transient transfection," wrote X.R. Ren and colleagues, Sun Yat Sen Zhongshan University.
They continued, "The present study was to determine whether the stable transfection of short hairpin RNA (shRNA)-producing vector could achieve potent and sustained inhibition of the HBV replication in 2.2.15 cells."
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Source: Gene Therapy Weekly (2006-06-01)
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