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Gene Therapy

In vivo gene transfer method to diabetic canine pancreas has been developed

Published in Gene Therapy Weekly, June 8th, 2006

Scientists have developed a method for the in vivo gene transfer to healthy and diabetic canine pancreas.

According to recent research from Spain, "Gene therapy may provide new treatments for severe pancreatic disorders. However, gene transfer to the pancreas is difficult because of its anatomic location and structure, and pancreatitis is a serious concern. Like the human pancreas, the canine pancreas is compact, with similar vascularization and lobular structure. It is therefore a suitable model in which to assess gene transfer strategies."

"We examined the ability of adenoviral vectors to transfer genes into the pancreas of dogs in which pancreatic...

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