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Cancer Treatment

Recent findings in cancer treatment described by researchers from Japan, the People's Republic of China and Sweden

Published in Gene Therapy Weekly, June 15th, 2006

Cancer treatment research advances have been reported from Japan, the People's Republic of China and Sweden.

Study 1: According to a study from Japan, cancer vaccine therapy improved using genetically modified dendritic cells (DCs) expressing tumor-associated antigen.

"The T-helper 1 (Th1) immune reaction is most important in DC-based immunotherapy. Interleukin 12 (IL-12) and granulocyte macrophage colony-stimulating factor (GM-CSF) play a pivotal role in inducing Th1 and cytotoxic T lymphocyte (CTL) responses.

"In this study, DCs expressing the natural tumor antigen gp70 of BALB/c-derived CT26 were adenovirally transduced with...

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