Published in Gene Therapy Weekly, June 15th, 2006
"GFAP is an intermediate filament protein present primarily in astrocytes. The gene is first expressed as astrocytes mature, and in the adult is strongly upregulated in response to CNS damage," wrote Y. Lee and colleagues, University of Alabama.
"Thus," they continued, "in addition to its astrocyte specificity, transcriptional regulation of the GFAP gene is of interest as a reporter of CNS signaling during development and injury."
"Several laboratories have shown that...
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