Drug Development
HIV-derived lentiviral vectors transduce murine cerebellar Purkinje cells
Published in Gene Therapy Weekly, June 15th, 2006
According to a study from Japan, "Cerebellar Purkinje cells are key elements in motor learning and motor coordination, and therefore, it is important to clarify the mechanisms by which Purkinje cells integrate information and control cerebellar function."
"Gene transfer into neurons, followed by the assessment of the effects on neural function, is an effective approach for examining gene function," said Takashi Torashima at Kanazawa University and collaborators. "However, this method has not been used fully in the study of the cerebellum because adenovirus vectors, the...
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Source: Gene Therapy Weekly (2006-06-15)
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