Cell Biology
New findings in cell biology described from Singapore and the United States
Published in Gene Therapy Weekly, July 6th, 2006
Study 1: According to research from Singapore, embryonic stem (ES) cell pluripotency is regulated by Oct4 and Nanog transcription networks.
"Oct4 and Nanog are transcription factors required to maintain the pluripotency and self-renewal of ES cells," wrote Y.H. Loh and colleagues, Genome Institute of Singapore.
"Using the chromatin immunoprecipitation paired-end ditags method, we mapped the binding sites of these factors in the mouse ES cell genome. We identified 1,083 and 3,006 high-confidence binding sites for Oct4 and Nanog, respectively....
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Source: Gene Therapy Weekly (2006-07-06)
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