Published in Gene Therapy Weekly, July 20th, 2006
Study 1: According to a study from Japan, inactivation of atypical protein kinase C (aPKC) lambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex.
"In developing mammalian telencephalon, the loss of adherens junctions and cell cycle exit represent crucial steps in the differentiation of neuroepithelial cells into neurons, but the relationship between these cellular events remains obscure.
"aPKC is known to contribute to junction formation in epithelial cells and to cell fate determination for...
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