Virology
Findings from the United States and Japan in virology provide new insights
Published in Gene Therapy Weekly, July 20th, 2006
Study 1: According to a recent study from the United States, dendritic cell (DC) maturation and function is altered by simian virus 5 (SV5).
"Human epithelial cells infected with the parainfluenza virus SV5 show minimal activation of host cell interferon (IFN), cytokine, and cell death pathways. In contrast, a recombinant SV5 P/V gene mutant (rSV5P/V-CPI-) overexpresses viral gene products and is a potent inducer of IFN, proinflammatory cytokines, and apoptosis in these cells," wrote S. Arimilli and colleagues, Wake Forest University.
They continued,...
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Source: Gene Therapy Weekly (2006-07-20)
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