Pancreatic Cancer Therapy
Pancreatic cancer cell growth rate is reduced by RNA interference suppression
Published in Gene Therapy Weekly, July 20th, 2006
"MUC1 is a highly glycosylated, type I transmembrane protein expressed by normal ductal epithelial cells of the pancreas, breast, lung, and gastrointestinal tract, and overexpressed in many cases of adenocarcinoma," wrote H. Tsutsumida and colleagues, University of Nebraska.
They continued, "We down-regulated MUC1 expression by RNA interference and investigated the effects on malignant and metastatic potential of a human pancreatic cancer cell line, S2-013."
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Source: Gene Therapy Weekly (2006-07-20)
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