Prostate Cancer Therapy

Prostate cancer cell growth inhibited by transient reduction of PTI-1 expression

Published in Gene Therapy Weekly, July 20th, 2006

According to recently published research from the People's Republic of China, transient reduction of prostate tumor-inducing gene 1 (PTI-1) expression by short interfering RNAs (siRNAs) inhibits the growth of human prostate cancer cell lines.

"PTI-1 was originally identified by differential ribonucleic acid (RNA) display in human prostate carcinoma. PTI-1 is expressed in human prostate carcinoma but not in benign prostate hypertrophy or normal prostate tissue.

"PTI-1 may be a member of oncogenes that could affect protein translation and contribute to carcinoma development in human prostate. To investigate the role of PTI-1 in human prostate...

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Source: Gene Therapy Weekly (2006-07-20)

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