Gene Therapy Weekly
Susan Hasty, Publisher
Table of Contents . . . July 27th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Antisense Technology - Transferrin receptor-targeted liposome efficiently delivers antisense DNA
Gene Transfer - Adenovirus-mediated gene transfer affects pulmonary artery vascular reactivity
Gene Transfer - Gene transfer achieved using modified cationic liposomes
RNA Research - Polyethylenimine fraction increases transfection efficiency
RNA Research - Small interfering RNA in human cells selectively localizes to target RNA sites
Allergy & Immunology - Defensins participate in innate defense against influenza A virus
Allergy & Immunology - Exogenous and endogenous TLR ligands activate anti-chromatin and polyreactive B cells
Allergy & Immunology - Subclasses of an anti-RhD antibody produced by transient expression in COS cells
Alzheimer Disease - Amyloid-like endonuclease fibrils display runaway domain swapping
Apoptosis - Induced prostate cancer cell apoptosis involves hydrogen peroxide production
Apoptosis - Leukemia cell-induced apoptosis is sensitized by MEK1 inhibition
Apoptosis - Melanoma cell apoptosis is induced by phosphorothioate oligodeoxy-nucleotide
Apoptosis - Taxol-induced apoptosis targets cellular FLICE-like inhibitory protein
Arthritis - Pathogenesis of rheumatoid arthritis may involve heat shock protein B8
Awards - Codexis awarded U.S. EPA's Presidential Green Chemistry Challenge Award
Breast Cancer - Breast cancer apoptotic responses are mediated by adiponectin
Breast Cancer - Breast cancer cell proliferation induced by prokinase-type plasminogen activator
Breast Cancer Genetics - BRCT domain characterized
Business Update - DNAPrint announces ancestry-testing program for dental patients
Business Update - DNAPrint Genomics CEO tells shareholders that "theranostic" drugs signal new era in medicine
Business Update - Epigenomics AG and Affymetrix announce strategic diagnostics platform agreement
Business Update - Euroscreen and Medarex announce license and research service agreement
Business Update - Sontra Medical signs agreement with JOYMG to distribute skin permeation system in South Korea
Business Update - Tercica tracks prescription rate of mecasermin injection for growth primary factor deficiency
Cancer Gene Therapy - Adenovirus-mediated gene therapy is promising for B cell malignancies
Cancer Gene Therapy - Apoptotic susceptibility endowed by induced expression of a fusion gene
Cancer Gene Therapy - Colon cancer cell proliferation and invasion impaired by gene knockdown
Cancer Gene Therapy - Herpes virus-mediated cancer gene therapy is weakly boosted by cell cycle drugs
Cancer Gene Therapy - Intradiabody-mediated phenotypic knockout enhances antiangiogenic effects
Cancer Gene Therapy - RNA electroporation generates cytolytic tumor-specific T cells
Cancer Gene Therapy - Urokinase plasminogen activator downregulation inhibits tumor invasion
Cardiology - Aprotinin affects downregulation of endogenous thrombin generation
Cell Biology - Prohibitin facilitates cellular senescence
Cell Biology - Receptor activity is modulated by extracellular protons
Collaborations - ChemGenex teams with MolecularMD to identify CML patients with T315I drug resistance mutation
Collaborations - Targeted Genetics enters new agreement to support ongoing HIV/AIDS vaccine development program
Colon Cancer - Induced colon cancer cell apoptosis involves a modulator protein
Critical Care Medicine - Glutamine regulates heat shock protein expression
DNA Research - A viral DNA polymerase factor dimerizes prior to nuclear translocation
DNA Research - Anti-DNA binding antibody hydrolyzes both double- and single-stranded DNAs
DNA Research - Novel quaternary domain interactions identified in a Hsp90 chaperone
DNA Research - Optical detection of DNA hybridization achieved
DNA Research - Pseudogenes capable of disease-causing gene conversion identified
DNA Vaccine - Ultrasound mediates DNA delivery by albumin-coated microbubbles
Developmental Biology - Coactivator of the retinoid X receptor alpha pathway upregulated
Developmental Biology - Insulin-like growth factor 1 functions in promotion of cell migration
Developmental Biology - Timing of puberty and plasma leptin levels is influenced by growth hormone
Developmental Biology - Zinc finger gene functions in erythroid and megakaryocytic differentiation
Diabetes Epidemiology - Sp1/Sp3 binding linked to glucose-dependent insulinotropic polypeptide receptor expression
Diabetes Pathogenesis - Connexin 43 downregulation induces senescence in glomerular mesangial cells
Diabetes Pathogenesis - Enzyme mutation perturbs insulin secretion
Diabetes Pathology - Protein mediates insulin-stimulated degradation of the insulin receptor
Diabetes Therapy - Gene transfer strategies for beta cell cytoprotection are focus of review
Diabetes Therapy - Lentivirus-transduced pancreatic islets provide long-term metabolic control
Down Syndrome - Children with Down syndrome are living longer, according to a new study
Drug Development - Experimental drug has the potential to treat a range of health problems from cancer to eye disease
Drug Development - Synthesis of psammaplin A improved
Endocrinology - Adipose cell interleukin release is regulated by thyroid-stimulating hormone
Gene Research - Cancer could be treated by therapies directed toward angiopoietin family genes
Genetics & Genomics - Cited2 loss affects placental trophoblast formation and vascularization
Genetics & Genomics - Dana Farber and 454 Life Sciences announce breakthrough in DNA sequencing for cancer research
Genetics & Genomics - Drosophila photoreceptor protein displays domain- and time-specific functions
Genetics & Genomics - Gene expression molecular signature identified in chronic myeloid leukemia
Genetics & Genomics - Germline transmission facilitated in genetically modified primordial germ cells
Genetics & Genomics - Specific gene expression mediated in nucleus pulposus cells
Genetics & Genomics - Spinal cord gene expression differs in radicular and neuropathic pain
Glial Tumors - Telomerase activity and hTERT mRNA expression in glial tumors clarified
Heart Transplant - Cardiac allograft survival prolonged by gene transfer of interleukin-17 receptor
Hemophilia A - Researchers find a key to a permanent genetic cure for hemophilia A patients
Hepatic Injury - Receptor agonists suppress concanavalin A-induced hepatic injury
Human Papillomavirus Vaccine - Human papillomavirus vaccine immunogenic and antiangiogenic
Human Papillomavirus Vaccine - Papillomavirus high-grade lesion regression stimulated by MVA E2 recombinant vaccine
Immunotherapy - Binding protein association modulates ecto-nucleotidase activity
Immunotherapy - Understanding CD8+ cell differentiation needed to develop effective immunotherapies
Infectious Diseases - Plasmodium falciparum antibodies demonstrate antiparasitic properties
Infectious Diseases - Pulmonary coccidioidomycosis resistance impaired by high interleukin-10 levels
Ischemia - Transient forebrain ischemia control genes screened in mouse hippocampus
Leukemia - B cell chronic lymphocytic leukemia response to nutlin-3 should be studied
Leukemia - Survival of transformed lymphocytes requires human T-cell leukemia virus gene
Liver Cancer - Murine liver cancer lymphatic metastasis is driven by caveolin-1
Liver Regeneration - Augmenter of liver regeneration regulates hepatocyte polyamine synthesis
Mesothelioma Epidemic - Genetic predisposition to fiber carcinogenesis cause of mesothelioma epidemic in Turkey
Microtechnology - Human growth hormone achieved using biodegradable polymeric microspheres
Muscle Atrophy - Gene therapy with anabolic growth factors may prevent muscle atrophy
Nephrology - Synthase overexpression alters epithelial hyaluronan distribution
Neuroscience - Brain-derived neurotrophic factor expression inhibits myogenic differentiation
Neuroscience - Ciliary neurotrophic factor gene expression regulated in Schwann cells
Neuroscience - Comparative plasticity of brain synapses determined in inbred mouse strains
Neuroscience - Developing axons and growth cones display RNA interference
Neuroscience - Methanol-induced oxidative stress disturbs the neuroimmune system
Neuroscience - Proteins and tumor suppressor convergence regulates cell cycle in neural cells
Neuroscience - Small GTPase is involved in neuronal activity-dependent dendritic development
Ophthalmology - Silencing acid-sensing ion channel 1a alters cone-mediated retinal function
Osteoarthritis - Gene therapy approaches for osteoarthritis are focus of review
Otorhinolaryngology - Otolith formation and semicircular canal development require separate genes
Parkinson Disease - Gene therapy and stem cell grafting as Parkinson disease therapies are reviewed
Patents - European Patent Office significantly limits scope of Kreutzer-Limmer RNAi patent claim
Progenitor Cells - Hematopoietic progenitor cell impairment involves down-modulation
Prostate Cancer - PTEN loss may prelude prostate cancer cell progression to androgen independence
Psoriasis - Identical rearrangements identified in angina and psoriasis vulgaris
RNA Research - Heterochromatin assembly and upkeep is independent of mammalian RNA interference
RNA Research - Small interfering RNAs display antiviral activity
Renal Cell Carcinoma - Renal carcinoma subgroups identified by differential gene expression
Sexual & Reproductive Health - Amino acid restriction affects amino acid transport in a placental cell line
Sexual & Reproductive Health - Maternal and embryonic transcripts selectively degraded
Stem Cell Research - Knockout mice were produced by mutagenesis in spermatogonial stem cells
Stem Cell Research - Notch controls stem cell proliferation and differentiation in dose-dependent manner
Stem Cell Transplantation - TNFd and IL-10 polymorphisms correlate with mortality in unrelated HCST
Tuberculosis - Mycobacterium tuberculosis age-related resistance facilitated by cytokines
Tumor Suppression - Tumor growth suppressed by ASPP2 cooperating with p53
Vector Development - Adenovirus types attach to and infect lymphocytes and monocytes
Vector Development - Chitosan-pEGFP nanoparticles provide transfection of primary chondrocytes
Vector Development - Hypoxia- and radiation-inducible retroviral vectors target breast cells
Vector Development - Strategies to improve nonviral vectors is outlined
Virology - Influenza A protein binding mediates protein kinase R inhibition
Allergies - Recent findings in allergies described by researchers from Japan, the United Kingdom and the United States
Angiology - Reports from Italy, Canada and the United States describe recent advances in angiology research
Atherosclerosis - Research from France and Netherlands add new data to atherosclerosis body of knowledge
Biomedical Engineering - Studies from Japan, Netherlands and the United States advance knowledge in biomedical engineering research
Breast Cancer - Recent findings from Japan and Greece illuminate research in breast cancer
Cancer Research - Researchers' data from the United States, People's Republic of China and Austria advance cancer research
Cancer Research - Studies from the People's Republic of China, South Korea and Germany add new findings to cancer body of knowledge
Cancer Treatment - Findings from Spain and the United States describe new data in cancer treatment research
Cancer Treatment - New findings from South Korea, Italy and United States in the area of cancer treatment detailed
Cancer Treatment - New findings from Sweden, the the Netherlands and Greece in the area of cancer treatment described
Cancer Treatment - New findings from the United States and Netherlands in the area of cancer treatment described
Cancer Treatment - Reports from the United States and Canada add new data to cancer treatment research
Cancer Treatment - Reports from the United States, United Kingdom and Germany add new data to cancer treatment research
Cancer Treatment - Researchers from the United States and Germany detail new studies and findings in the area of cancer treatment
DNA - Researchers from the United States, Brazil and Japan report recent findings in DNA
DNA - Researchers' findings from Israel, Japan and the United States advance DNA research
Gastroenterology - Studies from Canada, Greece and Japan add new findings to gastroenterology body of knowledge
Genetics - Findings from the United States and Canada describe new data in genetics research
Genetics - Findings from the United States and Iceland describe new data in genetics research
Genetics - Reports from Japan and the People's Republic of China advance knowledge in genetics research
Genetics - Research from the United States and Japan add new data to genetics body of knowledge
Genetics - Researchers' findings from the United States advance genetics research
Genetics - Studies from Italy and the United States describe new findings in genetics research
Genetics - Studies from Japan and Sweden add new findings to genetics body of knowledge
Hepatitis B Virus - New data from the People's Republic of China and Italy lluminates research in hepatitis B virus
Hepatitis C Virus - Recent studies from the People's Republic of China, Cuba and Spain add new data to hepatitis C virus research
Hepatitis C Virus - Studies from Japan, Belgium and the People's Republic of China add new findings to hepatitis C virus body of knowledge
Imaging - Researchers' data from Australia, Germany and the United States advance imaging research
Melanoma - New findings from Germany and Belgium in the area of melanoma detailed
Melanoma - New research from Switzerland and the United States in the area of melanoma detailed
Neurology - Recent findings from the United States and Canada illuminate research in neurology
Neurology - Researchers' findings from the People's Republic of China, Sweden and Canada advance neurology research
Papillomavirus - Studies from Mexico, Finland and Germany advance knowledge in papillomavirus research
Prostate Cancer - Findings from the United States describe new data in prostate cancer research
Prostate Cancer - New findings from Japan and the United States in the area of prostate cancer described
Transplants - Reports from Canada, Australia and the United Kingdom advance knowledge in transplants research
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