Published in Gene Therapy Weekly, July 27th, 2006
Study 1: Scientists have developed a soluble sustained release gene delivery system.
According to recent research from Israel, "Delivery of genetic substance to target cells remains an obstacle for efficient utilization of gene therapy approaches. In this study, we describe a formulation of methacrylate acid copolymer carrier of DNA, in which the release rate of the gene can be controlled by pH. Plasmid release was coupled with the polymer's dissolution, which was accelerated in alkali conditions. The released plasmid was intact and bioactive, although alteration from...
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