DNA Research
Pseudogenes capable of disease-causing gene conversion identified
Published in Gene Therapy Weekly, July 27th, 2006
"Pseudogenes are remnants of gene duplication (nonprocessed pseudogenes) and retrotransposition (processed pseudogenes) events. This study describes methods for identifying gene conversion candidates from predicted pseudogenes," wrote J.M. Bischof and colleagues, University of Iowa.
"Pseudogenes may accumulate and harbor sequence variations over time that become disease, causing mutations when transferred to genes by gene conversion. A total of 14,476 pseudogenes were identified, including 3,426 nonprocessed...
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Source: Gene Therapy Weekly (2006-07-27)
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