Published in Gene Therapy Weekly, July 27th, 2006
According to their report, "Osteoarthritis (OA) is common, debilitating, expensive, incurable, and very difficult to treat. Gene transfer to the synovial linings of affected joints is a promising strategy for achieving sustained, therapeutic, intra-articular concentrations of anti-arthritic gene products. This is not reasonably possible with existing, alternative technologies. The present review summarizes progress in achieving direct, in vivo intra-articular gene delivery and expression."
"Numerous non-viral vectors have been...
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