Developmental Biology
Tubulin-expressing Muller glia function in regeneration of zebrafish retina
Published in Gene Therapy Weekly, August 3rd, 2006
"Alpha 1T is a neuron-specific microtubule protein whose expression is induced in the developing and regenerating CNS. In the adult CNS, alpha 1T expression remains high in neural progenitors," wrote B.V. Fausett and colleagues, University of Michigan.
"Transgenic zebrafish harboring a 1.7 kb alpha 1T promoter fragment along with the first exon and intron express the transgene in a manner that recapitulates expression of the endogenous gene. We recently showed that this promoter...
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Source: Gene Therapy Weekly (2006-08-03)
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