Published in Gene Therapy Weekly, August 10th, 2006
"In heart failure (HF), ventricular myocardium expresses brain natriuretic peptide (BNP). Despite the association of elevated serum levels with poor prognosis, BNP release is considered beneficial because of its antihypertrophic, vasodilating, and diuretic properties.
"However, there is evidence that BNP-mediated signaling may adversely influence cardiac remodeling, with further impairment of calcium homeostasis," wrote H. Kogler and colleagues, University of...
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Source: Gene Therapy Weekly (2006-08-10)
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