Allergy & Immunology
Allergic inflammation is modified by different bacterial ligands in a rhinitis model
Published in Gene Therapy Weekly, August 10th, 2006
"It has been suggested that airway bacterial infections exacerbate allergic disorders, and bacterial components in the air affect allergic inflammation via Toll-like receptors expressed on mast cells and dendritic cells in the airway mucosa.
"Peptidoglycan (PGN) is a major component of the bacterial cell wall. We investigated the effect of PGN on the effector phase of allergic inflammation, in comparison with the effect of CpG-oligodeoxynucleotides (CpG), which is known to be a Th1 adjuvant," wrote K. Yamamoto and colleagues, Kyoto...
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Source: Gene Therapy Weekly (2006-08-10)
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