Gene Therapy Weekly
Susan Hasty, Publisher
Table of Contents . . . August 17th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Cancer Gene Therapy - Survivin downregulation enhances melanoma cell sensitivity to cisplatin
Cancer Gene Therapy - Telomerase-selective oncolytic adenoviral agent enhances antitumor efficacy
Gene Research - Late gene mutants of bacteriophage lambda are an efficient expression vector
RNA Interference - Measles virus and subacute sclerosing panencephalitis virus inhibited by RNA interference
Stem Cell Research - Stem cell factor fused with erythropoietin mimetic peptide expressed in Escherichia coli
Adenovirus Pathogenesis - Adenovirus type 2 and type 5 E1A genes are expressed at different levels
Alzheimer Disease - Amyloid beta-induced degeneration involves phosphorylation
Antitumor Therapy - Human-mouse chimeric antibody against transferrin receptor has a strong antitumor effect
Apoptosis - Apoptosis is rapidly induced in B-cell lymphoma by human antibodies
Apoptosis - Gastric cancer apoptosis inhibited by down regulating mitotic arrest deficient 2
Apoptosis - Tumor necrosis factor-related apoptosis induces ligand variants
Apoptosis - Tumor necrosis factor-related apoptosis-inducing ligand inhibits tumor growth
Arthritis - Noggin haploinsufficiency differentially affects arthritis tissue responses
Asthma - Topigen reports positive results in initial phase 2 trial of inhaled drug in asthma patients
Bladder Cancer - Cell Genesys launches expanded multiple-dose Phase 1 trial of CG0070 in recurrent bladder cancer
Breast Cancer - Mutant expression selectively suppresses breast tumors
Business & Finance - Genzyme delivers solid earnings growth based on strong top-line performance
Business Update - Agilent Technologies' high-resolution genomic coverage microarrays now available
Business Update - Clinical Data announces Familion Cardiac Channelopathy test milestone
Business Update - Entelechon receives BioChance Plus funding for a new method of protein quantification
Business Update - SurModics obtains rights to autoimmune antigens under distribution agreement with DIARECT AG
Cancer Gene Therapy - Adenovirus delivery augments treatment of metastatic carcinoma
Cancer Gene Therapy - Adenovirus transgene modification prevents p53 degradation
Cancer Gene Therapy - Adenovirus vector-mediated gene transfer achieved for hepatocellular carcinoma
Cancer Gene Therapy - Adenovirus-mediated therapy reduces the toxicity of oncolytic adenovirus
Cancer Gene Therapy - Antisense oligodeoxynucleotide inhibits growth of glioma cells
Cancer Gene Therapy - Antisense oligodeoxynucleotide-cisplatin treatment cures carcinoma xenografts
Cancer Gene Therapy - Cancer cell transduction enhanced by baculovirus-mediated tumor-homing peptides
Cancer Gene Therapy - Inducible nitric oxide synthase activity inhibits prostatic tumor growth
Cancer Gene Therapy - Mutated head and neck squamous cell carcinoma xenografts can be eradicated
Cancer Gene Therapy - Prostate cancer development suppressed by adenoviral-mediated vaccine
Cancer Gene Therapy - Pseudovirion gene delivery of a toxin treats human adenocarcinomas
Cancer Gene Therapy - Tumor growth suppressed by oncolytic adenovirus
Cancer Therapy - Angiogenesis clarified in a human neuroblastoma xenograft model
Cancer Therapy - Antiangiogenic therapy is enhanced with fusion proteins
Cancer Vaccine - Retrogen vaccine generates high titer survivin antibody responses
Cell Biology - Human high mobility group protein phosphorylated by a protein kinase
Cell Biology - Microtubule plus-end loading is not required for intracellular membrane traffic
Cell Biology - Papilloma protein abrogates shear stress-dependent survival in endothelial cells
Cell Biology - Tumor protein activity inhibited by sorting nexin
Colorectal Cancer - Thromboxane synthase upregulated in human colorectal carcinoma
DNA Vaccine - Cationic lipids for gene delivery in vitro and in vivo are reviewed
Developmental Biology - Growth and osteogenic differentiation of bone marrow stromal cells characterized
Developmental Biology - Rabbits can be generated from fibroblasts through nuclear transfer
Diabetes Pathogenesis - Diabetes-induced adenosine kinase decrease impairs T lymphocyte proliferation
Diagnostics - Bacterial reporter system evaluates human papillomavirus
Diagnostics - Combined method detects and differentiates enterovirus and coxsackievirus
Endocrinology - Follistatin isoform activity depends on differential cell surface binding
Endocrinology - Phenotypic aspects regulated in nontransformed intestinal epithelial cells
Enzymology - Endonuclease G functions in recombination and cellular proliferation
Finance - SurModics reports record Q3 2006 revenues of $18.1 million, up 10% over year ago
Genetics & Genomics - Coactivator cross-talk specifies transcriptional output
Genetics & Genomics - Constitutive expression affects myogenic cell proliferation and differentiation
Genetics & Genomics - Glycogen synthase kinase functions in inhibition of inflammatory gene expression
Genetics & Genomics - Nuclear respiratory factor senses changing cellular energy demands
Genetics & Genomics - Targets of aberrant hypermethylation identified in myeloid leukemia
HIV/AIDS Prevention - Tetraspanin domains inhibit macrophage infection by HIV
Head & Neck Cancer - Survivin targeting with adenoviral vectors used to treat head and neck squamous cell carcinoma
Healthcare Access - Experts explore how genomics could potentially be used to customize medical care
Hepatitis B Virus - Hepatitis B surface antigen-T-lymphocyte antigen fusion expressed using Pichia pastoris
Hepatitis C Virus - Hepatitis C virus nontranslated genomic cellular factors identified
Hepatocellular Carcinoma - CuraGen and TopoTarget announce initiation of Phase I/II trial of PXD101 for hepatocellular cancer
Immunomodulation - Immunosuppressant inhibits dendritic cell-mediated neutrophil chemoattraction
Ischemia - Chemokines are differentially regulated in mouse cardiac fibroblasts
Ischemia - Ischemic preconditioning protects cardiomyocytes against ischemic injury
Ischemia - Transporter expression is altered after ischemic reperfusion injury
Kidney Development - Multiple genes provide a link between kidney progenitor cells
Legal Issues - Enzo Biochem reports court ruling
Leukemia - Murine leukemia virus particles activate Rac1 in HeLa cells
Licensing Agreements - Tigris Pharmaceuticals enters licensing agreement with U.S. NIH to develop pro-drug for cancer
Marketing - Tasco Holdings hires OTC Financial Network to conduct investor relations campaign
Neuroblastoma - Integrative genomics identifies distinct molecular classes of neuroblastoma
Neuroscience - Phosphorylation enhances binding to isolated postsynaptic densities
Neuroscience - Translational repressor contribution to dendritic stress granules clarified
Obesity Pathogenesis - Adiponectin downregulates its own production and the expression of its receptor
Ophthalmology - Recombinant tissue plasminogen activator may penetrate the retinal veins
Osteosarcoma - Osteosarcoma cell lines and primary cells display different treatment sensitivities
Personnel - Brock Siegel, PhD, named chief operating officer of genome analysis company Solexa
Proteomics - Caenorhabditis elegans can screen for aging-related proteins
Proteomics - Human antimicrobial peptide LL-37 cloned and expressed in Escherichia coli
Reconstructive Surgery - Skin flap viability rallies with proangiogenic gene therapy treatment
Stem Cell Research - Stem cell factor fused with mimetic peptide in Escherichia coli
Vaccine Delivery - DNA delivery is mediated by beta-cyclodextrin embedded in polyelectrolyte multilayer
Vector Development - Adeno-associated viral vector poses little risk of germline transmission
Vector Development - Immunogenicity of cytopathic and noncytopathic viral vectors was examined
Vector Development - Method to purify adenovirus with arginine-glycine-aspartic acid-modified fibers has been developed
Virology - Influenza virus evades innate and adaptive immunity
Von Willebrand Disease - Lentiviral vectors expressing von Willebrand factor correct endothelial cells
Apoptosis - New data from the People's Republic of China and Taiwan lluminates research in apoptosis
Atherosclerosis - New findings from the United States in the area of atherosclerosis detailed
Breast Cancer - New research from France, the United States and Japan in the area of breast cancer detailed
Breast Cancer - Research from Germany and the United States in breast cancer provides new insights
Cancer Research - Findings from Finland, Japan and the United States advance knowledge in cancer research
Cancer Research - Recent studies from South Korea and Australia add new data to cancer research
Cancer Research - Reports from the United States and People's Republic of China describe recent advances in cancer research
Cancer Research - Researchers from Canada, the People's Republic of China and the United States publish new studies and findings in the area of cancer
Cancer Research - Researchers from the United States and Japan report details of new studies and findings in the area of cancer
Cancer Treatment - Data from Japan, Brazil and China advance knowledge in cancer treatment research
Cancer Treatment - Researchers from the United States and Italy report recent findings in cancer treatment
Cardiology - Data from Germany, the United States and the People's Republic of China advance knowledge in cardiology research
Colorectal Cancer - Researchers from Germany, Denmark and the United States describe findings in colorectal cancer studies
Gene Therapy - Researchers' work from India, Australia and Germany adds to gene therapy body of knowledge
Genetics - Findings from France and the United States in genetics provide new insights
Genetics - New findings from Italy, the United States and Norway in the area of genetics described
Genetics - Recent findings in genetics described by researchers from the United Kingdom, Russia and Netherlands
Heart Attack - New findings from Denmark, Austria and the United States in the area of heart attack described
Hepatitis B Virus - Researchers from France, Germany and Italy detail new studies and findings in the area of hepatitis B virus
Imaging - Recent findings in imaging described by researchers from Taiwan and the United States
Leukemia - Findings from the United States advance knowledge in leukemia research
Leukemia - Research from Germany and Sweden add new data to leukemia body of knowledge
Neurology - New data from Germany, the United States and Italy lluminates research in neurology
Neurology - Recent findings in neurology described by researchers from Japan, Australia and the United States
Neurology - Researchers from the United States report details of new studies and findings in the area of neurology
Physiology - New findings in physiology described from the United States and Japan
Renal Cancer - Studies from Japan and France advance knowledge in renal cancer research
Transplants - Researchers from Japan, the United States and France detail new studies and findings in the area of transplants
Vectors - Reports from the United States, Israel and United Kingdom add new data to vectors research
Vectors - Research from Taiwan, the United Kingdom and Turkey in vectors provides new insights
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