Published in Gene Therapy Weekly, August 17th, 2006
"Type I interferons (e.g. IFN alpha 2b) have been successfully used to treat a variety of hematological malignancies, but have not been efficacious for treatment of most solid tumors.
"We tested the hypothesis that delivery of type I interferon utilizing recombinant adenovirus (rAd) vectors may improve treatment efficacy of metastatic carcinomas by providing increased interferon exposure resulting from continuous transgene expression," wrote E. Brin and colleagues of Canji,...
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