Published in Gene Therapy Weekly, August 17th, 2006
"The disadvantage of a bacteriophage X expression system is that the replicated lambda DNA containing a foreign gene is coated by a phage head, and cell lysis occurs before sufficient expression of the cloned gene. The late genes of the bacteriophage X system are related to lambda DNA packaging and host cell lysis," wrote J.S. Oh and colleagues, Seoul National University.
"This study investigated the late gene mutants of the bacteriophage X in an attempt to develop an efficient expression vector system. The...
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