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Developmental Biology

Rabbits can be generated from fibroblasts through nuclear transfer

Published in Gene Therapy Weekly, August 17th, 2006

According to recently published research from the People's Republic of China, rabbits can be generated from fibroblasts through nuclear transfer.

"Somatic cell nuclear transfer offers new opportunities for genetic engineering and genome preservation in mammalian animal species. We show that, in addition to cumulus cells, cultured adult rabbit fibroblasts are also capable of supporting full-term development after nuclear transfer," wrote S.G. Li and colleagues, Shanghai Jiao Tong University..

"Nuclear transfer embryos constructed using serum-starved fibroblasts showed a significantly higher developmental rate than non-starved fibroblasts through...

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