Alzheimer Disease
Amyloid beta-induced degeneration involves phosphorylation
Published in Gene Therapy Weekly, August 17th, 2006
"Deposition of fibrillar amyloid beta (fA beta) plays a critical role in Alzheimer disease (AD). We have shown recently that fA ss-induced dystrophy requires the activation of focal adhesion proteins and the formation of aberrant focal adhesion structures, suggesting the activation of a mechanism of maladaptative plasticity in AD," wrote L. Heredia and colleagues, Instituto de Investigacion Medica Mercedes y Martin Ferreyra/Consejo Nacional de Investigaciones Cientificas y Tecnicas.
"Focal...
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Source: Gene Therapy Weekly (2006-08-17)
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