Diet & Nutrition
Hepatocarcinogenesis unaffected by hepatocyte growth factor in a Cho-deficient diet
Published in Gene Therapy Weekly, August 24th, 2006
"HGF is a promising agent for the treatment of intractable liver disease, due to its mitogenic, anti-apoptotic, and anti-fibrotic effects. We investigated the effect of recombinant human HGF (rh-HGF) on the development of both hepatocellular carcinoma (HCC) and preneoplastic nodules in rats fed a CDAA diet, an animal model of hepatocarcinogenesis resembling human development of HCC with cirrhosis," wrote C. Nakanishi and colleagues, Kyoto University Hospital.
"From weeks 13 to 48 of...
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Source: Gene Therapy Weekly (2006-08-24)
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