Published in Gene Therapy Weekly, September 7th, 2006
"Cell-mediated immunity is important for anti-Candida host defence in mucosal tissues. In this study we used cytokine-specific gene knockout mice to investigate the requirement for T helper type 1 (Th1) and Th2 cytokines in recovery from oral candidiasis," wrote C.S. Farah and colleagues, University of Queensland.
"Knockout mice used in this study included interleukin-4 (IL-4), IL-10, IL-12p40, interferon-gamma (IFN-gamma), and tumor necrosis factor (TNF). The mice were challenged either...
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Source: Gene Therapy Weekly (2006-09-07)
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