Published in Gene Therapy Weekly, September 7th, 2006
"SVN is a novel anti-HIV protein isolated from aqueous extracts of the cultured cyanobacterium Scytonema varium. SVN contains two apparent domains, one comprising amino acids 1-48 and the second stretching from amino acids 49 to 95," wrote C.Y. Xiong and colleagues, National Cancer Institute.
"These two domains display significant homology to each other and a similar pattern of disulfide bonds. Two DNA constructs encoding scytovirin 1-48 (Cys-7-Ser) (SD1) and 49-95 (Cys-55-Ser) (SD2) were constructed, and expressed in E....
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