Neuroscience
Airway-related neurons express nicotinic acetylcholine receptor subunits
Published in Gene Therapy Weekly, September 7th, 2006
"Nicotine acting centrally increases bronchomotor tone and airway secretion, suggesting that airway-related vagal preganglionic neurons (AVPNs) within the rostral nucleus ambiguus (rNA) express nAChRs. In the present study, we examined the three main functionally characterized subtypes of nAChRs in the CNS, the alpha 7 homomeric and alpha 4 beta 2 heteromeric receptors," wrote O. Dehkordi and colleagues, Howard University.
"First, we characterized the expression of these subunits at the...
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Source: Gene Therapy Weekly (2006-09-07)
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