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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . September 14th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Apoptosis - Breast cancer cell apoptosis and growth inhibition induced by truncated cadherin

Cancer Therapy - Transcription factor overexpression sensitizes cells to antimitotic agents

Cardiology - Cardiac ventricular action potential is unaffected by simulated outward current

Gene Research - Gene transfer achieved with poly-melittin peptides

Neuroscience - Effects of salvinorin A are abolished in opioid receptor knockout mice

Adverse Drug Reaction - Acetaminophen hepatotoxicity is influenced by c-jun N-terminal kinase

Age-Related Macular Degeneration - Experimental choroidal neovascularization is controlled by gene therapy

Apoptosis - Apoptotic cells detected using a paramagnetic lipidic coating

Apoptosis - Tumor necrosis factor-related apoptosis-inducing ligand sensitizes tumors

Atherosclerosis - Rapid arterial wall lipid deposition facilitated by lipoprotein lipase expression

Autism - Autism Consortium launches first comprehensive study to discover the genetic causes of autism

Breast Cancer - Breast cancer growth inhibited by superoxide dismutase overexpression

Business Update - Correlagen automates genetic testing with new platform

Business Update - Four studies affirm significance of Monogram's Trofile HIV co-receptor tropism assay

Business Update - Stratagene, Merck subsidiary enter agreement to develop and license RNA purification system

Cancer Gene Therapy - Alveolar rhabdomyosarcoma gene expression signature identified

Cancer Gene Therapy - An immunological synapse allows tumor targeting by vector particles

Cancer Gene Therapy - Bladder cancer adenovirus-mediated gene therapy modeled

Cancer Gene Therapy - Breast cancer-associated gene absence increases expression of axis members

Cancer Gene Therapy - Malignant breast cancer cell cycle arrest induced by downregulation

Cancer Therapy - Cancer immunotherapy by interleukin-21 evaluated in a mathematical model

Cancer Therapy - Circulating dendritic cells studied in resected high-risk cutaneous melanoma

Cancer Therapy - Human p53 transcription regulation maintains cell cycle checkpoints

Cancer Therapy - Mammary tumor potential targets identified

Cancer Therapy - Melanoma cell immune evasion requires a signaling pathway

Cancer Therapy - Sphingosine kinase inhibitors display antitumor activity

Cardiology - Cardiac differential regional gene expression induced by free wall pacing

Cell Biology - Angiotensin pathway may be involved in sclerosis in aging tissues

Cellular Therapy - Practical approach for cell-based liver disease therapy remains difficult

Cervical Cancer - siRNA proposed as a novel radiation/chemotherapy-sensitizing agent

Chemotherapy - Combined chemotherapy-virotherapy inhibits multidrug-resistant phenotype

Colon Cancer - Colon carcinoma cell molecular target identified

Colorectal Cancer - Colorectal cancer cell telomere attrition produced by telomerase inhibition

Critical Care Medicine - Cell-mediated immune response after burn improved by lack of aromatase

DNA Vaccine - Gene delivery with mannosylated lipoplex provides efficient gene transfer

Developmental Biology - Sarcoma cell growth isoform production induces vasculogenesis

Developmental Biology - Tumor and normal cells cultured in microcapsules studied

Diet & Nutrition - Fatty acids enhance fatty acid oxidation in myotubes

Drug Delivery - PEOz-b-PLLA diblock polymeric micelles proposed as drug carriers for cancer therapy

Embryonic Stem Cell Research - Melanocytes can be induced from embryonic stem cells

Endocrinology - Endocrine cell proglucagon gene expression regulated by exchange protein

Finance - Tm Bioscience signs agency agreement for unsecured warrants, debentures worth $6.24 million

Finance - Transgenomic Inc. begins trading on Nasdaq, granted 180 days more to regain compliance

Gastroenterology - Colitis ameliorated by extracellular superoxide dismutase gene transfer

Gastroenterology - Intestinal epithelium iron uptake influenced by microglobulin apical distribution

Gene Expression - Decline in exogenous gene expression correlates with plasmid DNA degradation

Gene Research - Multiple target genes affected by short hairpin RNAs

Gene Research - Scleroderma fibroblast epigenetic repression influenced by collagen expression

Gene Silencing - Translation repression by microRNA-induced gene silencing requires a helicase

Genetics & Genomics - Cumulus-oocyte complex gene-expression profile obtained

Genetics & Genomics - Duplicated regions of the human genome display heritability of polymorphisms

Hepatitis C Virus - Near full-length hepatitis C virus genome cloned from clinical samples

Hepatocellular Cancer - Hepatocellular carcinoma autoantibodies analyzed proteomically

Hepatology - Hyposulfatemia is associated with altered cholesterol metabolism

Hepatology - Liver-specific growth factor overexpression enhances somatic growth

Immunotherapy - B cell signaling control involves regulation of receptor internalization

Infectious Diseases - Bacterial pathogens causing bloodstream infections identified by DNA microarray

Inflammatory Bowel Disease - Inflammatory bowel disease epithelial inflammation reduces T cell modulation

Kidney Disease - Vascular calcification and renal osteodystrophy influence chronic kidney disease

Liposarcoma - Liposarcoma cell releases superoxide dismutase suppresses tumors

Melanoma - Melanoma development promoted by epigenetic PTEN silencing

Multiple Sclerosis - Chromos updates progress on development of CHR-1103 for treatment of multiple sclerosis

Myocardial Infarction - Cell transplants for myocardial infarction work better with apoptosis prevention therapy

Myocardial Infarction - Myocardial infarct size is reduced in models given proangiogenic gene therapy

Natural Products - Dihydronitidine exhibited tumor specific cytotoxicity

Nephrology - Gene function suppressed in renal proximal tubules by RNA interference

Nephrology - Kidney membrane vesicle gamma-hydroxybutyrate transport clarified

Nephrology - Oxidative signaling in renal epithelium requires cytosolic phospholipase

Neurology - Functioning of Parkinson disease-associated enzyme rescued by Parkin

Neuroscience - Mediation of anticonvulsant and sedative effects of loreclezole clarified

Neuroscience - Neuronal cell death rescued by restoration of receptor physiological levels

Neuroscience - Preprotachykinin-A gene promoter modulation is induced by neurotrophin

Neuroscience - Selective inhibition of plasma kallikrein protects brain from reperfusion injury

Personnel - Molecular diagnostics company XDx appoints James P. Yee, MD, PhD, as chief medical officer

Personnel - Sigma-Aldrich names Rich Keffer, JD, as general counsel and secretary

Proteomics - Human nitric oxide synthase expression is regulated by signaling

Proteomics - Protein kinase targeted in an interleukin regulatory pathway

Proteomics - Retinoic acid receptor effects on tumor cell growth mediated via RhoA inhibition

Proteomics - Transcription factor targeting suppresses vascular permeability and inflammation

RNA Research - Regulatory RNAs have limited role in stress gene regulation in Salmonella

Respiratory Medicine - Cell cycle progression in lung fibroblasts requires kinase activation

SARS - SARS coronavirus ectodomain amino acids induce neutralizing antibodies

Sarcoidosis - Sarcoidosis progression is not associated with toll-like receptor polymorphism

Stem Cell Research - Hematopoietic progenitor cells protected by telomerase reverse transcriptase

Stem Cell Research - Suppression of hematopoietic cell growth occurs synergistically

Thrombosis - Antithrombotic properties of an inhibitor of coagulation cascade clarified

Transplantation Biology - Transplanted human stem cell rejection does not involve natural killer cells

Tuberculosis - Xenomics begins patient enrollment in monitoring study of test for diagnosing tuberculosis

Vector Development - Dendritic cationic lipids with charged headgroups provide efficient gene delivery

Vector Development - Methacrylamide polymers with hydrolysis-sensitive side groups act as degradable gene carriers

Allergies - Researchers from the United States and Japan report recent findings in allergies

Apoptosis - Recent findings in apoptosis described by researchers from Switzerland, the United States and Germany

Apoptosis - Researchers' work from Japan, France and Canada adds to apoptosis body of knowledge

Apoptosis - Studies from the United Kingdom, Italy and Australia describe new findings in apoptosis research

Biomedical Engineering - Studies from Japan, Netherlands and the United States describe new findings in biomedical engineering research

Breast Cancer - New data from Germany and the United States lluminates research in breast cancer

Breast Cancer - New findings from Australia and the United States in the area of breast cancer described

Breast Cancer - New findings from Germany, the United States and Greece in the area of breast cancer described

Breast Cancer - New findings in breast cancer described from France, the United States and cjen@sun

Breast Cancer - New research from Germany, the United States and Spain in the area of breast cancer detailed

Breast Cancer - Reports from the United States and South Korea describe recent advances in breast cancer research

Cancer Research - Findings from the United States and People's Republic of China describe new data in cancer research

Cancer Research - Reports from Finland and Japan describe recent advances in cancer research

Cancer Research - Research from the United States, Canada and Japan in cancer provides new insights

Cancer Research - Researchers from the United States report recent findings in cancer

Cancer Research - Researchers' data from Italy and Germany advance cancer research

Cancer Research - Researchers' findings from Finland, the United States and the People's Republic of China advance cancer research

Cancer Research - Studies from the People's Republic of China and United States describe new findings in cancer research

Cancer Treatment - Findings from Italy and the United States advance knowledge in cancer treatment research

Cancer Treatment - New findings in cancer treatment described from the United States and Australia

Cancer Treatment - Reports from the United States, Japan and Cuba add new data to cancer treatment research

Cardiology - Findings from the United States in cardiology provide new insights

Cardiology - Studies from Japan, Germany and the United States advance knowledge in cardiology research

Cell Biology - New findings in cell biology described from Italy, Germany and the United States

DNA - Recent studies from the United States and Australia add new data to DNA research

DNA - Reports from Canada, the United States and France add new data to DNA research

DNA - Studies from Israel, Turkey and Germany advance knowledge in DNA research

Developmental Biology - Studies from Japan, the South Korea and the United States describe new findings in developmental biology research

Diabetes - Findings from the United States advance knowledge in diabetes research

Diabetes - Recent findings in diabetes described by researchers from Netherlands, United States and Germany

Diabetes - Researchers from Ireland, the United States and Italy report recent findings in diabetes

Diabetes - Researchers' work from Germany, the United States and Japan adds to diabetes body of knowledge

Genetics - Data from the United States, Taiwan and Japan advance knowledge in genetics research

Genetics - New data from Belgium, the People's Republic of China and Japan lluminates research in genetics

Genetics - New data from Japan and Germany lluminates research in genetics

Genetics - New research from the United States and Canada in the area of genetics detailed

Genetics - Recent findings from Japan, Luxembourg and the United States illuminate research in genetics

Genetics - Reports from the United States and Japan advance knowledge in genetics research

Genetics - Researchers from Italy, the United States and Norway report recent findings in genetics

Genetics - Researchers from the United Kingdom, United States and Netherlands detail new studies and findings in the area of genetics

Genetics - Researchers' findings from Japan, Germany and the United States advance genetics research

Genetics - Researchers' work from the United States and Japan adds to genetics body of knowledge

HIV/AIDS - Reports from Canada, the United States and Spain add new data to HIV/AIDS research

Hepatitis B Virus - Researchers from France, Germany and the People's Republic of China publish new studies and findings in the area of hepatitis B virus

Imaging - New findings in imaging described from the United States and South Korea

Lung Cancer - Research from Netherlands and United States in lung cancer provides new insights

Neurology - Researchers from Japan and Italy report details of new studies and findings in the area of neurology

RNA - Findings from the People's Republic of China and United States describe new data in RNA research

RNA - New findings from the United States in the area of RNA described

RNA - Studies from the United Kingdom and United States describe new findings in RNA research

Tuberculosis - New data from the United States and France lluminates research in tuberculosis

Vectors - New findings from the United States and Germany in the area of vectors described

Vectors - Researchers from Japan and the United States provide details of new studies and findings in the area of vectors

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