Immunotherapy
Pneumocystis pneumonia host response requires chemokines
Published in Gene Therapy Weekly, September 21st, 2006
"We have previously shown that Tc1 CD8+ T cells have in vitro and in vivo effector activity against PC infection in mice. Because these cells have preferential expression of CXCR3, we investigated whether CXCR3 was required for host defense activity against PC," wrote F. McAllister and colleagues, University of Pittsburgh.
"Mice deficient in CXCR3 but CD4+ T cell intact, showed an initial delay but were able to clear the infectious challenge, indicating that CXCR3 signaling is not essential for clearance of PC. CD4-depleted mice had lower levels...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2006-09-21)
More Articles from Gene Therapy Weekly
- Cardiology
Myofibril organization involves muscle-specific protein - Lung Cancer
Lung cancer suppressed by RNA interference targeting pituitary transforming gene - Nephrology
Accelerated tubular cell aging occurs in senescence marker protein knockout mice - Neuroscience
Synaptotagmin silencing inhibits fast exocytosis and endocytosis - Allergy & Immunology
Myosin heavy chain phosphorylation coincides with mast cell degranulation - Angiology
Thromboplastin sensitivity to clotting factors can be modulated - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
