Published in Gene Therapy Weekly, September 21st, 2006
Researchers in the United States conducted a study "to compare the transduction efficiency of a lentiviral vector in the retina of normal mice and retinal degenerative (rd) mice following subretinal injection at various postnatal ages."
"Subretinal injections of lentiviral vector (pHR-CMV-GFP, 107IU/mL) were performed in normal (C57/6J) and rd mice on postnatal days P1 to P7 using a trans-scleral method and on days P14-P35 by a trans-corneal method. One to six weeks later the eyes were prepared for histological analysis. GFP...
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