Gene Therapy Weekly

Age-Related Macular Degeneration - Age-related macular degeneration is controlled by antiangiogenic gene therapy

Cancer Therapy - Combination rapamycin-chemotherapy sensitivity and resistance determined

Genetics & Genomics - Specific domains required for origin recognition complex nuclear localization

Glioma - Malignant glioma DNA silencing targets revealed by epigenomic profiling

RNA Interference -  Caenorhabditis elegans RNA interference requires ATP-binding cassette transporters

AAT Deficiency - Extensive post-license data reaffirm clinical safety profile of Prolastin

Adipogenesis - Increased triplet repeat-binding protein predisposes to impaired adipogenesis

Allergy & Immunology - Repeated allergen challenge involves RANTES regulation of airway responsiveness

Apoptosis - Apoptosis protein inhibitor antagonized by alpha-fetoprotein

Apoptosis - Pancreatic beta-cell apoptosis involves transcription factor activation

Apoptosis - Pancreatic beta-cell mediated death requires proapoptotic molecule

Atherosclerosis - Atherosclerotic plaque stability is affected by novel candidate genes

Awards - Talecris Biotherapeutics announces recipients of 2006 European ALTA fellowships

Breast Cancer - Breast cancer cells affected by a negative cell cycle regulator

Breast Cancer - Breast cancer diminished survival correlates with topoisomerase expression

Business Update - Cerepro files response to EMEA review

Business Update - Chromos announces independent multiple sclerosis advisory board

Business Update - CombiMatrix announces commercial launch of its first molecular diagnostic test

Business Update - CytoGenix scientists to publish book chapter

Business Update - ExonHit produces new map for human genome expression, tools for its study

Cancer Gene Therapy - Anti-glioma tumor immunity enhanced by lysate-pulsed dendritic cells

Cancer Gene Therapy - Cancer gene therapy based on virology and immunology reported

Cancer Gene Therapy - Cancer gene therapy developed based on novel adenovirus vectors

Cancer Gene Therapy - Chimeric immunoreceptor displays colon cancer antitumor activity

Cancer Gene Therapy - Immunogene therapy of cancer achieved with transfected dendritic cells

Cancer Gene Therapy - Pancreatic islet cells specifically targeted by viral-conjugated reporter genes

Cancer Immunotherapy - FcR gamma expression not required for HeFi-1-mediated tumor growth inhibition

Cancer Therapy - Cancer cell pro-metastasis is mediated by a transduction pathway

Cancer Therapy - Human breast carcinoma cells are affected by a histone deacetylase inhibitor

Cancer Therapy - Molecularly targeted anticancer agent combinations optimized

Cancer Therapy - Orthotopic human breast tumors cured by targeted bacterial therapy

Cardiac Medical Devices - Conor Medsystems announces two-year follow-up data from EuroSTAR pivotal study

Cardiology - Cardiac effects of enzyme replacement therapy for mucopolysaccharidosis probed

Cardiology - Cardiac hypertrophy affected by a kinase inhibitor

Cardiology - Recombinant factor VIIa use in cardiac surgery produces no adverse effects

Cervical Cancer - Heat shock factor targeted by RNA interference

Collaborations - Lentigen announces second collaborative research agreement with University of Pennsylvania

Colon Cancer - Colon cancer cell growth inhibited by fragile histidine triad protein

Dermatology - Dermal endothelial cell P-selectin is mediated by interleukin

Developmental Biology - Follicular development can be affected by an oral contraceptive

Diabetes Control - Insulin responses are inhibited by resveratrol

Diabetes Therapy - Type 1 diabetes glucose metabolism affected by recombinant protein

Endocrinology - Alkylated thiazolidinones are follicle-stimulating hormone receptor agonists

Gene Research - Introgen Therapeutics and Gendux, AB, announce EU orphan designation for Advexin therapy

Gene Research - Regeneron receives National Institutes of Health grant as part of knockout mouse project

Genetics & Genomics - Hematopoietic cell proliferation may be mediated by protein modulation

Genetics & Genomics - Hox gene silencing is influenced by an oncogene

HIV/AIDS Prevention - Early steps of HIV-1 replication inhibited by integration with viral integrase

Helicobacter Pylori -  Helicobacter pylori induces heparin-binding epidermal growth factor expression

Herpes Simplex Virus - Herpes simplex virus hydrophobic helices enhance virus infection and fusion

Human Growth Hormone - Emisphere's eligen technology demonstrates delivery of active recombinant human growth hormone

Hurler Syndrome - Gene therapy in dog model of Hurler syndrome was examined

Immunotherapy - Antitumor immune responses are mediated by natural killer T cells

Leukemia - T cell acute lymphoblastic leukemia/lymphoma target identified

Licensing Agreements - SurModics and X-Cell Medical sign license agreement for drug eluting stent development

Lung Cancer - Non-small cell lung cancer finds new potential therapy in ADAM inhibition

Market Analysis - Research and Markets releases triple analysis of next generation therapies in oncology

Medical Tests - U.S. FDA drafts regulatory guidance to industry and labs for group of medical tests

Mergers & Acquisitions - CyGenics acquires stake in DNAPro in exchange for Cell Sciences subsidiary

Multiple Sclerosis - Multiple sclerosis T cell repertoire is similar in childhood and adult onset

Nephrology - Fabry disease-associated renal decline lessened by enzyme replacement therapy

Nephrology - Fulminant hepatic failure modeled by induced murine liver damage

Neuroscience - A neuroprotectant inhibits mitochondrial membrane depolarization

Neuroscience - Expression of vesicular glutamate transporter neuron immunoreactivity defined