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Bone apposition occurs to biocoated titanium implants

Published in Gene Therapy Weekly, October 12th, 2006

According to a study from Germany, bone apposition occurs to titanium implants biocoated with recombinant human bone morphogenetic protein-2 (RhBMP-2).

"The aim of the present study was to investigate bone formation to rhBMP-2-biocoated and rhBMP-2-nonbiocoated titanium implants after implantation in dogs," wrote J. Becker and colleagues, University of Dusseldorf.

"Implantation of sand-blasted and acid-etched (C), chromosulfuric acid surface-enhanced (CSA), and rhBMP-2-biocoated CSA [BMP-A: noncovalently immobilized rhBMP-2 (596 ng/cm2), BMP-B: covalently immobilized rhBMP-2 (819 ng/cm2)] implants was performed in both the...

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