Published in Gene Therapy Weekly, October 12th, 2006
"BMPs are secreted signaling molecules, which play a major role in kidney development and disease. Here, we show the existence of mRNA for BMP-2 and for the BMP receptors BMPR1A, BMPR1B, BMPRII, ACVR1A, ACVR2, and ACVR2B in differentiated mouse podocytes and the protein expression of BMPR1A in human glomerular podocytes," wrote G. Pache and colleagues, Clinical University of Munster.
"BMP-2 dose dependently increases the free cytosolic Ca2+ concentration in...
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