Gene Therapy Weekly
Susan Hasty, Publisher
Table of Contents . . . October 26th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Cancer Gene Therapy - Transporter expression profiled in childhood T cell acute lymphoblastic leukemia
Endocrinology - Prolactin overexpression in differentiating mammary gland induces benign lesions
Gene Delivery - Adenoviral vector-mediated gene delivery toxicity evaluated
Genetics & Genomics - Abelson helper integration site gene functions in a variant of T cell lymphoma
Nephrology - Kidney cell epidermal growth factor receptor transactivation is receptor mediated
Acute Myeloid Leukemia - Leukemogenic AML1-ETO-targeted proteins identified
Adenovirus Vector - Adenoviral vectors encoding bone morphogenetic protein-2 retarded bone formation
Adenovirus Vector - Gene therapy increases survival in glycogen storage disease type Ia
Adenovirus-Mediated Gene Therapy - Replication-defective recombinant UGT1A adenovirus selectively restores hepatic UGT1A function
Antibacterial Agents - Escherichia coli expresses antimicrobial fusion peptide
Apoptosis - Antigen presentation pathways contribute differentially to vaccinia virus immunogenicity
Apoptosis - Apoptosis protection conferred by mitochondrial isocitrate dehydrogenase
Apoptosis - Apoptotic gene expression profiled in chronic lymphocytic leukemia
Apoptosis - Bladder carcinoma cell apoptosis induced by combined treatment
Apoptosis - Colon carcinoma-induced apoptosis promotes the endoplasmic reticulum stress response
Apoptosis - Hepatocyte apoptosis induction by hepatitis B virus produces different effects
Apoptosis - p53 apoptosis inhibited by interaction with high mobility group proteins
Apoptosis - Tumor cell resistance to induced apoptosis involves autocrine-paracrine loop
Asthma - Nonallergic asthma circulating cytokeratin autoantibodies studied
Brain Cancer - Autocrine/paracrine platelet-derived growth factor regulates neural progenitor cell proliferation
Brain Cancer - EpiCept announces successful Phase I trial in brain cancer for Azixa (MPC6827)
Breast Cancer - Breast cancer cell drug resistance is differentially affected
Breast Cancer - Breast cancer cell estrogen receptor alpha regulated by forkhead box protein
Breast Cancer - Breast cancer resistance protein purification elucidated
Breast Cancer - Breast cancer-endothelial cell fusions involve syncytin
Business Update - Asklepios Biopharmaceutical inks cross license agreement with GlaxoSmithKline
Business Update - Diagnostic Hybrids announces release of Analyte Specific Reagent (ASR) for metapneumovirus
Business Update - Mirus Bio introduces RNAi tool with hydrodynamic technology to analyze gene function in vivo
Cancer Gene Therapy - Glioma virotherapy enhanced by inhibiting innate immune responses
Cancer Gene Therapy - Intraarterial gene delivery treats hepatic tumors
Cancer Gene Therapy - Murine carcinoma therapeutic efficacy improved by combination treatment
Cancer Gene Therapy - Pancreatic cancer cell apoptosis enhanced by Bcl-XL antisense oligonucleotides
Cancer Gene Therapy - Primary breast cancer therapy achieved using nonreplicating adenoviral vector
Cancer Therapy - Astrocytoma growth and vascularity influenced by ganglioside distribution
Cancer Therapy - Breast cancer cells affected by insulin-like growth factor binding protein
Cancer Therapy - Cholangiocarcinoma neoplastic cell growth modulated by estrogens
Cancer Therapy - Medulloblastoma cell invasion can be inhibited
Cancer Therapy - Normal and malignant human urothelial cells differ in TRAIL susceptibility
Cancer Therapy - Osteopontin inhibits macrophage nitric oxide synthesis to enhance tumor proliferation
Cancer Therapy - Targeted therapy achieved using recombinant vesicular stomatitis virus
Cell Biology - Microtubule binding and clustering occurs in enzyme-deficient yeast
Collaborations - Cenix BioScience and Merck KGaA sign framework agreement for RNAi-based drug discovery
Colon Cancer - EXACT Sciences continues deliberations regarding revised colorectal cancer screening guidelines
DNA Research - Bacterial DNA adenine methyltransferases selectively inhibited
DNA Research - Translesion DNA synthesis across a cell adduct documented
Dental Research - Reduced alveolar bone mass and dentin dysplasia displayed in transgenic mice
Developmental Biology - Embryonic development is affected by leptin
Developmental Biology - Ligand functions in mammalian oogenesis and folliculogenesis
Developmental Biology - Oocyte developmental competence is enhanced by secreted factors
Drug Delivery - Insulin delivery achieved using novel microcapsules
Drug Delivery - Targeted drug delivery achieved by focal disruption of the blood-brain barrier
Drug Development - SCOLR Pharma announces achievement of milestone with Wyeth Consumer Healthcare
Endocrinology - Activin and inhibin production are regulated in seminiferous epithelium
Endocrinology - Insulin-like actions displayed by a naphthoquinone derivative
Enzymology - Ca2+/calmodulin-dependent protein kinase phosphatase mutationally analyzed
Enzymology - Nitric oxide synthase is nonselectively inhibited by L-Arg chlorination
Enzymology - Protein kinases activated by mammalian transforming growth factor kinase
Enzymology - Ubiquitin-conjugating enzyme displays thiolester formation
Finance - CytRx awarded federal grant to explore novel type 2 diabetes and obesity treatment
Gene Research - ATP-binding cassette transporter enhances phagocytosis of macrophage apoptotic cells
Genetics & Genomics - Cell cycle regulatory genes targeted by p53-mediated transcriptional repression
Genetics & Genomics - Nebulin gene mutations associated with autosomal recessive nemaline myopathy
Genetics & Genomics - Rapid genotyping of common deficient alleles achieved by DNA-microchip technique
HIV/AIDS Pathogenesis - HIV targeting to B cells defined
HIV/AIDS Research - Sangamo reports positive data on treating HIV with zinc finger DNA-binding protein nucleases
Hepatitis A Virus - Hepatitis A virus virological course determined in real time
Hunter Syndrome - Enzyme replacement therapy with idursulfase evaluated in Hunter syndrome
Immunotherapy - Immunomodulatory oligonucleotides as novel therapy for breast cancer
Immunotherapy - S100A8 triggers oxidation-sensitive repulsion of neutrophils
Immunotherapy - T cell-mediated regulation of colitis involves adenosine receptors
Kaposi Sarcoma Pathogenesis - Kaposi sarcomagenesis involves stimulation of tuberin phosphorylation by G protein-coupled receptor
Kaposi Sarcoma-Associated Herpesvirus Pathogenesis - Kaposi sarcoma-associated herpesvirus K10/10.1 protein may affect mRNA stability in host cells
Liver Cancer - Hepatic carcinogenesis is influenced by isomerase expression
Lung Transplantation - Gene transfection can modify transplanted lung to prevent injury
Melanoma - Melanoma cell cyclin expression is regulated by kinase signaling
Mergers & Acquisitions - Inyx to acquire Pharmapac UK, Ltd.
Myocardial Infarction - Acute myocardial infarction protection is conferred by endogenous adrenomedullin
Myocardial Infarction - Celera identifies genetic polymorphism associated with increased risk for myocardial infarction
Nephrology - Diabetic nephrology is influenced by connective tissue growth factor
Neuroscience - Dendritic morphology is regulated by developmental expression of a co-activator
Neuroscience - Hippocampal levels are affected by growth hormone replacement
Neuroscience - Neurodegenerative disorders involve modulation of heat shock protein function
Neuroscience - Neurofibroma-like phenotypes induced through transforming growth factor signaling
Neuroscience - Rho-kinase inhibition enhances axonal regeneration after peripheral nerve injury
Ophthalmology - Clinical trials in Leber's hereditary optic neuropathy to start in Germany and U.K.
Prostate Cancer - Prostate cancer xenografts give way to RNA interference
Proteomics - B cell toll-like receptor repertoire is directly activated
Proteomics - Functional proteomics identifies targets for the MAP kinase pathway
Proteomics - Ghrelin receptor activity characterized in a pituitary cell line
Proteomics - Membrane progestin receptors characterized in transfected cells
Proteomics - Permeabilized mammalian cells function as an experimental system
Proteomics - Recombinant antibodies deplete abundant proteins from human serum
Respiratory Medicine - Recombinant human activated protein C improves pulmonary function
Stem Cell Research - Cancer stem cells exist in thyroid cancer
Stem Cell Research - Embryonic stem cell developmental potency is not improved by nuclear transfer
Stroke - Stroke models receive benefits from therapy combining gene therapy with marrow cells
Virology - Gammaherpesvirus persistence alters key CD8 T cell memory characteristics
Virology - Influenza A virus NS1 protein does not suppress mammalian cell RNA interference
Virology - Viral interleukin-induced signaling is abrogated by a single-chain antibody
Alzheimer Disease - Researchers from the United States, New Zealand and Hungary provide details of new studies and findings in the area of Alzheimer disease
Apoptosis - Data from , Canada and Netherlands advance knowledge in apoptosis research
Apoptosis - Research from the United States and Japan add new data to apoptosis body of knowledge
Apoptosis - Researchers from the United States and 807 Taiwan describe findings in apoptosis studies
Atherosclerosis - Findings from the United Kingdom, Japan and Italy in atherosclerosis provide new insights
Cancer Research - Data from the United Kingdom, South Korea and United States advance knowledge in cancer research
Cancer Research - Recent studies from Japan, France and Finland add new data to cancer research
Cancer Research - Researchers from the United Kingdom, Finland and United States detail new studies and findings in the area of cancer
Cancer Research - Researchers from the United States and South Korea publish new studies and findings in the area of cancer
Cancer Treatment - Findings from Finland, the United Kingdom and Germany advance knowledge in cancer treatment research
Cancer Treatment - New findings from the United States and Japan in the area of cancer treatment described
Cancer Treatment - New research from the United States and People's Republic of China in the area of cancer treatment detailed
Cancer Treatment - Researchers from the United States and Germany describe findings in cancer treatment studies
Cancer Treatment - Studies from Israel, Canada and the United States advance knowledge in cancer treatment research
Cardiology - New findings from the United States and United Kingdom in the area of cardiology described
Cardiology - New findings from the United States in the area of cardiology detailed
Cardiology - Reports from the United States, Japan and Switzerland add new data to cardiology research
DNA - Researchers from the United States and Australia detail new studies and findings in the area of DNA
Developmental Biology - Reports from the United States and Japan advance knowledge in developmental biology research
Diabetes - Data from the United States advance knowledge in diabetes research
Diabetes - Reports from Canada, Ghana and the United States advance knowledge in diabetes research
Diet & Nutrition - Reports from Australia, Brazil and Denmark add new data to diet & nutrition research
Drug Delivery - Data from the United States and Japan advance knowledge in drug delivery research
Endocrinology - Studies from the United States and Germany describe new findings in endocrinology research
Genetics - New findings from the United States, United Kingdom and Japan in the area of genetics detailed
Genetics - New findings in genetics described from the United States and People's Republic of China
Genetics - Researchers from Japan, Belgium and the United States report recent findings in genetics
HIV/AIDS - Findings from France, the United States and Germany in HIV/AIDS provide new insights
Heart Disease - Researchers from Japan, Taiwan and the United Kingdom report recent findings in heart disease
Ischemia - Findings from the United States, India and United Kingdom advance knowledge in ischemia research
Nephrology - Recent studies from Netherlands, South Korea and Denmark add new data to nephrology research
Nephrology - Reports from Japan, Denmark and the United States add new data to nephrology research
Neurology - Data from the People's Republic of China, France and United States advance knowledge in neurology research
Prostate Cancer - Recent studies from the United States add new data to prostate cancer research
Prostate Cancer - Reports from the United States and People's Republic of China advance knowledge in prostate cancer research
Prostate Cancer - Studies from the People's Republic of China, Japan and Canada add new findings to prostate cancer body of knowledge
Proteins - Recent findings in proteins described by researchers from the United States and France
SARS - Researchers from Singapore, Italy and the People's Republic of China report recent findings in SARS
Vectors - Recent findings in vectors described by researchers from the United States
Vectors - Reports from the United States and Netherlands add new data to vectors research
Virology - Studies from the United States and Taiwan describe new findings in virology research
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