Published in Gene Therapy Weekly, October 26th, 2006
Study 1: A study from the United States has documented the reduction of infarct size in a rat model of regional myocardial ischemia and reperfusion by a synthetic peptide.
"The increased mobilization of iron and copper during ischemia is reported to contribute to postischemic injury. DMI-4983 is a small synthetic peptide, Asp-Ala-His-Lyes (DAHK), that mimics the high-affinity copper-binding site of the N-terminus of human albumin.
"This peptide was reported to inhibit copper-induced formation of reactive oxygen species in vitro, reduce...
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