Published in Gene Therapy Weekly, October 26th, 2006
"Interactions between tumor cells and their host environment can play a major role in regulating survival programs required for tumor progression. OPN is a glycophosphoprotein overexpressed by tumors, and is a key molecule for tumor progression and metastasis. OPN also inhibits expression of autocrine and paracrine inducible nitric oxide synthase (iNOS).
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