Published in Gene Therapy Weekly, October 26th, 2006
"We have previously shown that stimulation of extracellular signal-regulated protein kinase (ERK) by BK in murine inner medullary collecting duct (mIMCD)-3 cells is mediated by EGFR transactivation. The mechanism of EGFR transactivation seemed to be novel, because it does not require phospholipase C, Ca2+, calmodulin, protein kinase C, G alpha(i) subunits, or EGFR-B-2 receptor heterodimerization," wrote Y.V. Mukhin and colleagues, Medical University of South Carolina.
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Source: Gene Therapy Weekly (2006-10-26)
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