NewsRx

Search our medical news database

Nephrology

Kidney cell epidermal growth factor receptor transactivation is receptor mediated

Published in Gene Therapy Weekly, October 26th, 2006

A study from the United States has reported that collagenase-2 and-3 mediate epidermal growth factor receptor (EGFR) transactivation by bradykinin (BK) B-2 receptor in kidney cells.

"We have previously shown that stimulation of extracellular signal-regulated protein kinase (ERK) by BK in murine inner medullary collecting duct (mIMCD)-3 cells is mediated by EGFR transactivation. The mechanism of EGFR transactivation seemed to be novel, because it does not require phospholipase C, Ca2+, calmodulin, protein kinase C, G alpha(i) subunits, or EGFR-B-2 receptor heterodimerization," wrote Y.V. Mukhin and colleagues, Medical University of South Carolina.

...

Want to see the full article?

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Buy Now


Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Gene Therapy Weekly


NewsRx is Social

Follow us on your favorite social network by clicking on a button below:

Follow NewsRx on Twitter

NewsRx on Facebook

Awards

eHealthcare Leadership 2011 Winner
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

  • Google 2010 PageRank: #2 Among Top Health News and Media Publications
  • Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
  • Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
  • Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
NewsRx on Facebook