Reconstructive Surgery
Transduced endothelial progenitor cells promote vessel growth in ischemic flaps
Published in Gene Therapy Weekly, November 2nd, 2006
"Neovascularization occurs through two mechanisms: angiogenesis and vasculogenesis. Therefore, there are two strategies to promote neovascularization: therapeutic angiogenesis and therapeutic vasculogenesis (endothelial progenitor cells therapy)," investigators in the People's Republic of China reported.
"In this study, we examined whether or not endothelial progenitor cells combined with vascular endothelial growth factor (VEGF) gene therapy is useful for ischemia surgical flaps in vivo. At the same time, we quantitatively compared the neovascularization ability...
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Source: Gene Therapy Weekly (2006-11-02)
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