Published in Gene Therapy Weekly, November 2nd, 2006
"Overexpression of P-glycoprotein (P-gp), the product of the MDR1 gene, might complement chemotherapy and radiotherapy in the treatment of tumors. However, for safety and mechanistic reasons, it is important to know whether MDR1 overexpression influences the expression of other genes.
"Therefore, we analyzed differential gene expression in cells of the human lymphoblast cell line TK6 retrovirally transduced with MDR1 using the GeneChip Human...
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Source: Gene Therapy Weekly (2006-11-02)
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