Published in Gene Therapy Weekly, November 9th, 2006
Study 1: According to a recent study from Japan, the docking protein Crk-associated substrate (Cas) links Tyr phosphorylation signaling to elongation of cerebellar granule cell axons.
"Cas is a tyrosine-phosphorylated docking protein that is indispensable for the regulation of the actin cytoskeletal organization and cell migration in fibroblasts. The function of Cas in neurons, however, is poorly understood," wrote J. Huang and colleagues, Riken Brain Science Institute.
"Here we report that Cas is dominantly enriched in the brain, especially...
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