Published in Gene Therapy Weekly, November 9th, 2006
Study 1: A study from the United States has documented that in vivo restoration of physiological levels of truncated TrkB.T1 receptor rescues neuronal cell death in a trisomic mouse model.
"Imbalances in neurotrophins or their high-affinity Trk receptors have long been reported in neurodegenerative diseases. However, a molecular link between these gene products and neuronal cell death has not been established," wrote S.G. Dorsey and colleagues, National Cancer Institute.
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